We are a company based in Uruguay with a subsidiary in the United States, dedicated to researching plant extracts. Our studies are conducted in collaboration with the Department of Life Sciences and Oncology at Ben-Gurion University, one of the most important scientific research departments in Israel.
This department is also internationally recognized, collaborating with leading centers in several countries, including Switzerland, the United States, and Australia.
Osigma is committed to research to make significant discoveries that contribute to improving health and saving lives.
About us
Our company is dedicated to researching plant extracts for application in human and animal health.
We have a committed and dedicated multidisciplinary team covering various stages, from fieldwork and product manufacturing to research.
Currently, our research team is led by a renowned scientist from Ben-Gurion University in Israel, Professor Varda Shoshan-Barmatz, who specializes in cancer research.
Professor Varda Shoshan-Barmatz
2 Nobel Prize nominations in Chemistry and Life Sciences.
Professor of Molecular Physiology in the Department of Life Sciences and Hyman-Kreitman Professor of Bioenergetics at Ben-Gurion University in Israel.
Professor Shoshan-Barmatz was the founder of the National Institute of Biotechnology in the Negev (NIBN) and its director for 10 years. She has received several awards, including the Teva Pharmaceutical Industries Founder’s Award in recognition of her pioneering scientific achievements in cancer research.
She earned a PhD in Biochemistry from the Weizmann Institute of Science and completed postdoctoral studies at the University of Wisconsin-Madison, USA, and the University of Toronto.
Scientific team of Dr. Varda Shoshan-Barmatz
Juan Manuel Ortas
Scientist & Founding Partner
Cristian Desmarchelier
Scientific advisor
Complementary studies
Anticancer activity in a plant extract
As a result of the research conducted by the team led by Prof. Varda Soshan-Barmatz, this article has been published in the prestigious scientific journal MDPI (Multidisciplinary Digital Publishing Institute).
U.S. Provisional Patent Application No. 63/435,684
Treaty of Berne: Certificate of Invention
The Berne Treaty is an international treaty focused on the protection of copyright. Its first text was signed on September 9, 1886, in Bern, Switzerland. It has been completed and revised several times, and was last amended on September 28, 1979. As of March 2018, 176 States are parties to the Convention.
Toxicity Study
This study, in compliance with ISO 10993-11, evaluated our plant extract in CD-1 mice using repeated doses via oral gavage. It complied with FDA Good Laboratory Practices, ensuring the quality and reliability of the results.
Complementary studies
Sao Paulo Studio
A study of the aerial parts of the Vernonanthura nudiflora plant. Researchers conducted a detailed analysis of the plant’s chemical components and evaluated its antiproliferative and antioxidant properties. The results of the study are significant.
Cordoba Study
Academic study on research into the reproduction and cultivation of the species Vernonanthura nudiflora and Lessingianthus mollissimus. It includes detailed information on their botanical description, natural habitat, behavior in an artificial environment, and response to domestication techniques.
MEV Monograph
MEV has beneficial health properties, especially in the treatment of cancer, and has no side effects or interactions with other medications. The study was led by Dr. Bernardo Udaquiola and his multidisciplinary team.
Proapoptotic and anticancer activity of the hydroethanolic extract of Vernonanthura Nudiflora
The National Institutes of Health (NIH), part of the U.S. Department of Health and Human Services, is the nation’s leading medical research agency, making important discoveries that improve health and save lives.
✅ PMID: 36900417
✅ DOI: 10.3390
✅ PMCID: PMC10000589
This study was published in
Other articles
The Times – Israel’s Times Against Cancer
A research team from Ben-Gurion University in Israel has discovered antitumor properties in plant extracts in cell culture studies and mouse models. The plant extract has been shown to be effective in inhibiting tumor growth and eliminating cancer cells. The team plans to conduct human trials in the future.
BGU Scientists Find Possible Cancer Breakthough
The chemistry of Vernonanthura nudiflora
